| Type: | supporting |
| Age Range: | 16 – 27 |
| Gender: | female |
| Voice Part: | spoken |
| Vocal Range: | none |
| Dancing: | N/A |
| Name | Gender | Vocal Part | Age Range | Role Type |
| Agrippa | male | spoken | 30 – 40 | supporting |
| Alexas | female | spoken | 20 – 40 | cameo |
| Camidius | male | spoken | 35 – 50 | supporting |
| Canidus | male | spoken | 25 – 40 | cameo |
| Charmian | female | spoken | 25 – 40 | supporting |
| Cleopatra | female | spoken | 33 – 47 | lead |
| Clown | male | spoken | 20 – 40 | cameo |
| Decretas | male | spoken | 20 – 40 | cameo |
| Demetrius | male | spoken | 30 – 50 | cameo |
| Diomedes | male | spoken | 25 – 40 | supporting |
| Dolabella | male | spoken | 21 – 33 | supporting |
| Enobarbus | male | spoken | 25 – 35 | supporting |
| Eros | male | spoken | 25 – 35 | supporting |
| Gallus | male | spoken | 25 – 45 | cameo |
| Iras | female | 21 – 35 | supporting | |
| Maecenas | male | spoken | 25 – 50 | cameo |
| Marcus Aemilius Lepidus | male | spoken | 30 – 50 | supporting |
| Mardian | male | spoken | 25 – 45 | cameo |
| Mark Antony | male | spoken | 33 – 47 | lead |
| Menas | male | spoken | 20 – 30 | supporting |
| Menecrates | male | spoken | 20 – 30 | cameo |
| Octavius Caesar | male | spoken | 26 – 38 | lead |
| Philo | male | spoken | 30 – 50 | cameo |
| Pompey | male | spoken | 21 – 32 | supporting |
| Proculeius | male | spoken | 22 – 35 | supporting |
| Scarus | male | spoken | 18 – 30 | supporting |
| Seleucus | male | spoken | 35 – 55 | supporting |
| Silius | male | spoken | 30 – 40 | cameo |
| Taurus | male | spoken | 30 – 45 | chorus |
| The Soothsayer | male | spoken | 30 – 50 | supporting |
| Thidias | male | spoken | 25 – 35 | cameo |
| Varrius | male | spoken | 20 – 30 | cameo |
| Ventidius | male | spoken | 28 – 40 | supporting |